Research articles

Medical research scientists are working around Australia and the globe to better understand neurological conditions and their causes, seeking new or better treatments and ultimately, cures. Here are details of current research projects and exciting discoveries in the field of neurological research.

MSWA recommends that you discuss any research results, or new treatments mentioned, with your neurologist; as they know your individual circumstances and can provide personalised advice.

Repurposing existing medications for remyelination in MS

Researchers from the International Progressive MS Alliance, through their BRAVEinMS platform, have screened 1,280 medications that have already been through clinical trials and deemed safe. Three of these drugs were found to promote remyelination, an important step in generating new myelin sheaths around axons in the adult central nervous system for people with MS.

MSWA contributes funds annually to support the research efforts of the International Progressive MS Alliance; $1m has been allocated for 2021.

Read MS Australia's article

A robotic step forward for physical stroke rehabilitation

US researchers are using a robotic exoskeleton to provide high-dose therapy early after stroke to maximise physical mobility when neuroplasticity allows the greatest benefits. This study offers insights for the timelines for gait therapy to begin after recovering from stroke, and the use of assisted technologies to do so.

Read ScienceDaily's article

New study describes non-invasive way to track Huntington’s disease progression

A development from the US has seen an opportunity to track disease progression through MRI brain scans that could potentially measure blood in the brain. Researchers propose the use of this non-invasive test as a biomarker before patients begin showing symptoms.

Read Oxford Academic's article

Vocal music boosts the recovery of language functions after stroke

Listening to music every day could improve language recovery after acute stroke according to University of Helsinki researchers. When comparing vocal music, instrumental music and audiobooks, vocal music was seen to positively impact the structural connectivity of the language network in the left frontal lobe.

Read ScienceDaily's article

New imaging technique may boost research in biology, neuroscience

Researchers from Harvard University present a new imaging technique to produce high-quality, deep-tissue images without sacrificing time. Using an infrared laser to penetrate through biological tissue, the light excites the fluorescent molecules which emit signals that the microscope captures to form the image.

Read ScienceDaily's article

Severity of MS could be predicted through respiratory functions

A new study has indicated that the strength of muscles while exhaling could indicate physical ability and MS severity. Conclusions suggested that impaired respiratory muscle strength was associated with lower functional capacity and more severe disease progression.

Read MS News Today's article

Researchers find Mediterranean diets are good for the brain

A recent study from the US displayed positive outcomes of a Mediterranean dietary approach on cognitive aging and neurogenerative disease specifically for MS. Another group of German researchers also contend that a Mediterranean diet might protect against memory loss associated with Alzheimer’s.

MSWA funded researcher Associate Professor Lucinda Black has conducted research that previously had similar findings. Professor Black continues to research MS and diets. Visit our Commitment to Research page to read more.

Read ScienceDirect's MS article  |  Read ScienceDaily's Alzheimer's article

Smartwatch sensors monitor real-world motor fluctuations in Parkinson’s disease

Researchers driven by Apple Inc., have developed an ambulatory monitoring system to track dyskinesia (involuntary movements) and resting tremors. Remote monitoring of motor symptoms could enable more precise treatments according to recent research.

Read Science Translational Medicine's article

Role of sleep-related brain activity in clearing toxic proteins and preventing Alzheimer's disease

Evidence of sleep-dependent low-frequency global brain activity in the clearance of Alzheimer's disease-related toxin build-up is presented in new research. This neuronal activity was more strongly linked with cerebrospinal fluid flow in healthy controls than higher risk groups and patients, and the findings could serve as a potential imaging marker for clinicians in evaluating patients.

Read ScienceDaily's article

Canadian research indicates perinatal stroke as a source of insight into plasticity development

Researchers have considered the diverse long-term neurological outcomes associated with perinatal brain injury. Non-invasive brain stimulation through transcranial magnetic stimulation and therapeutic habilitation are key interventions that may make perinatal stroke a model for human developmental plasticity.

Read the full article

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